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All had previously received at least one purine analogue or alkylatingagent.
2
The role of hyperthermia during regional alkylatingagent chemotherapy is controversial.
3
Standard therapy for MM has been an alkylatingagent and corticosteroid.
4
Thiotepa is an alkylatingagent widely used in high-dose chemotherapy.
5
Treatment with this alkylatingagent chemically compromises alkyl-DNA repair functions.
Использование термина alkylators на английском
1
HDAC inhibitors, DNA alkylators and nucleoside analogs are effective components of combination chemotherapy.
2
On the other hand, the use of alkylators and topoisomerase II inhibitors is associated with an increased risk of t-AML.
3
The protein level of MRP1 correlated with cellular resistance to busulfan and chlorambucil, and Rom exposure sensitized cells to these DNA alkylators.
4
To determine a possible mechanism of their synergism, we analyzed the effects of HDAC inhibitors on the expression of drug transporters which export DNA alkylators.